Top 10 Best ergonomic keyboards and mice in 2025

Introduction

Looking for a reliable ergonomic keyboards and mice in 2025? You’re not alone. With so many models available today, it’s easy to get lost—especially when descriptions are vague or customer reviews are all over the place. That’s why we decided to sort things out. Not by claiming to know everything, but by analyzing what sells well, what real users say, and what’s worth your attention both on paper and in practice. Our goal isn’t to drown you in technical details, but to guide you toward the best possible choices—without wasting hours comparing on your own. In short, a practical and hopefully useful guide.

See the full ranking

Our Top 3

PromoN° 1
Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Keys Ergonomic Keyboard with Wrist Rest and 3-Level DPI Adjustable Wireless Ergonomic Mouse for Windows, Mac OS Desktop/Laptop/PC(Black)
  • 【Wave Ergonomic Wireless Keyboard and Mouse Combo】The wireless keyboard features a wave key and wrist rest design that naturally fits your fingers and relieves wrist strain. The adjustable stand allows you to set the keyboard to the most comfortable height, making it ideal for long-term use. Note: The USB receiver is located on the back of the mouse.
  • 【Wireless Optical Mouse】The wireless mouse is designed with comfort in mind, featuring a contoured shape that fits snugly in the palm and complements the natural curve of your right hand. All controls are easily within reach. This mouse is equipped with forward and back functions, allowing you to navigate the web faster and more efficiently than ever before.
  • 【Plug-and-Play 2.4G Wireless Connection】One 2.4 GHz USB receiver can connect both the keyboard and mouse, or they can be used separately. Plug and play—no software download is required. The 2.4 GHz wireless connection offers a strong and reliable signal up to 33 feet (10 meters), without delays.
  • 【Automatic Power Saving Function】The ULSOU wireless keyboard and mouse combo features an automatic power-saving function. After 30 seconds of inactivity on the keyboard and 15 minutes of inactivity on the mouse, both devices enter sleep mode to conserve battery life. This greatly extends battery life, and any button press will activate the devices again. The keyboard requires 1 AA battery, and the mouse requires 1 AA battery. (batteries not included).
  • 【Wide Compatibility and Dual System Layout】This wireless keyboard and mouse combo is compatible with Windows XP/Vista/7/8/10/11, Mac, and other operating systems. It’s suitable for desktops, Chromebooks, PCs, laptops, and more. You can switch between Windows and macOS by pressing FN+Q or FN+W.
N° 2
Logitech Wave Keys MK670 Combo, Wireless Ergonomic Keyboard with Signature M550 L Wireless Mouse, Comfortable Natural Typing, Bluetooth, Logi Bolt, for Multi-OS, Windows/Mac - Graphite
  • Meet the comfort combo: Get comfier with the Wave Keys Ergonomic Wireless Keyboard paired with the Signature M550 L Wireless Mouse - a great fit for medium- to large-sized hands
  • Compact keys: Wave Keys’ compact size allows you to bring your mouse closer to your body, resulting in a more natural shoulder position compared to a full size keyboard
  • Type in comfort all day long: The wavy design of this compact keyboard places your hands, wrists and forearms in a natural typing position for all-day comfort
  • More palm support, less pressure: A cushioned palm rest with memory foam gives you more wrist support throughout the day (1)
  • Less noise, more focus: On top of its sculpted design and rubber grip, this quiet mouse uses SilentTouch technology to make workdays more peaceful with 90% less click noise (7)
N° 3
MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size, Windows/Mac/Computer/Laptop, Black DirectorC
  • 【DIRECTOR-C SPLIT KETBOARD】Designed to minimize strain and discomfort in your hands, wrists, and arms, this keyboard is split into two halves, allowing each hand to type at a comfortable angle and distance, so you can say goodbye to excessive reaching and twisting. Please note: The USB-C is not a receiver and cannot be used on its own, it is an adapter that needs to be plugged into a USB-A receiver in order to work. (Connection distance within 33 feet)
  • 【LARGE SIZE STANDARD ERGONOMIC AND FULL SIZE LAYOUT】Designed with a concave curve, which conforms to the natural shape of the hands and fingers, reducing strain and fatigue. In addition, each key is slightly angled to promote a more natural typing motion and further alleviate stress on your fingers, hands, and wrists. Keyboard(19.09*10.04*1.83inch)Mouse (2.87*4.09*2.28inch)
  • 【PILLOWED WRIST REST】Featured a pillowed palm rest, providing support and comfort for the hands and wrists. Made of a soft, non-slip material, preventing slippage and enhancing stability during typing. It reduce the risk of developing musculoskeletal disorders associated with prolonged keyboard use.
  • 【VERTICAL ERGONOMIC MOUSE】Unique vertical design offers optimal ergonomics, with adjustable DPI settings (800/1200/1600/2400)to suit various tasks and preferences, ensuring accuracy and speed when needed, a silent switch, and a side-scrolling wheel, catering to all your needs. The mouse and keyboard share a common USA-A receiver.
  • 【RECHARGEABLE AND LONG LASTING】 Featuring a 500mAh and 500mAh rechargeable battery in both the keyboard and mouse, providing long-lasting performance for extended use. The battery holds power for up to 1-2 months of usage on a single full charge. You can focus on work and worry less about charging. (Charge your keyboard and mouse before you use them. We recommend using the 5V 1A charging specification.).

How to choose a good ergonomic keyboards and mice?

On the surface, choosing a ergonomic keyboards and mice seems simple. But once you dig in, it gets more complicated. Between technical differences, unfamiliar brands, and unclear features, it’s better to ask the right questions:

  • Usage: Will you use it daily or only occasionally? That heavily influences the right model.
  • Budget: No need to go for the most expensive one right away. What matters is the value for money.
  • Key factors:
    • Durability, build quality, lifespan
    • Truly useful features (not just marketing buzz)
    • User reviews, especially after weeks or months
    • Availability of customer service in case of issues

We’ve cross-checked multiple sources: Amazon data, detailed reviews, search trends… and a bit of intuition too—because numbers don’t tell the whole story. This mix allows us to build our ranking, which we update regularly. The goal isn’t to just list names but to guide you toward what truly works.

Our Top 10 Best ergonomic keyboards and mice

PromoN° 1
Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Keys Ergonomic Keyboard with Wrist Rest and 3-Level DPI Adjustable Wireless Ergonomic Mouse for Windows, Mac OS Desktop/Laptop/PC(Black)
  • 【Wave Ergonomic Wireless Keyboard and Mouse Combo】The wireless keyboard features a wave key and wrist rest design that naturally fits your fingers and relieves wrist strain. The adjustable stand allows you to set the keyboard to the most comfortable height, making it ideal for long-term use. Note: The USB receiver is located on the back of the mouse.
  • 【Wireless Optical Mouse】The wireless mouse is designed with comfort in mind, featuring a contoured shape that fits snugly in the palm and complements the natural curve of your right hand. All controls are easily within reach. This mouse is equipped with forward and back functions, allowing you to navigate the web faster and more efficiently than ever before.
  • 【Plug-and-Play 2.4G Wireless Connection】One 2.4 GHz USB receiver can connect both the keyboard and mouse, or they can be used separately. Plug and play—no software download is required. The 2.4 GHz wireless connection offers a strong and reliable signal up to 33 feet (10 meters), without delays.
  • 【Automatic Power Saving Function】The ULSOU wireless keyboard and mouse combo features an automatic power-saving function. After 30 seconds of inactivity on the keyboard and 15 minutes of inactivity on the mouse, both devices enter sleep mode to conserve battery life. This greatly extends battery life, and any button press will activate the devices again. The keyboard requires 1 AA battery, and the mouse requires 1 AA battery. (batteries not included).
  • 【Wide Compatibility and Dual System Layout】This wireless keyboard and mouse combo is compatible with Windows XP/Vista/7/8/10/11, Mac, and other operating systems. It’s suitable for desktops, Chromebooks, PCs, laptops, and more. You can switch between Windows and macOS by pressing FN+Q or FN+W.
N° 2
Logitech Wave Keys MK670 Combo, Wireless Ergonomic Keyboard with Signature M550 L Wireless Mouse, Comfortable Natural Typing, Bluetooth, Logi Bolt, for Multi-OS, Windows/Mac - Graphite
  • Meet the comfort combo: Get comfier with the Wave Keys Ergonomic Wireless Keyboard paired with the Signature M550 L Wireless Mouse - a great fit for medium- to large-sized hands
  • Compact keys: Wave Keys’ compact size allows you to bring your mouse closer to your body, resulting in a more natural shoulder position compared to a full size keyboard
  • Type in comfort all day long: The wavy design of this compact keyboard places your hands, wrists and forearms in a natural typing position for all-day comfort
  • More palm support, less pressure: A cushioned palm rest with memory foam gives you more wrist support throughout the day (1)
  • Less noise, more focus: On top of its sculpted design and rubber grip, this quiet mouse uses SilentTouch technology to make workdays more peaceful with 90% less click noise (7)
N° 3
MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size, Windows/Mac/Computer/Laptop, Black DirectorC
  • 【DIRECTOR-C SPLIT KETBOARD】Designed to minimize strain and discomfort in your hands, wrists, and arms, this keyboard is split into two halves, allowing each hand to type at a comfortable angle and distance, so you can say goodbye to excessive reaching and twisting. Please note: The USB-C is not a receiver and cannot be used on its own, it is an adapter that needs to be plugged into a USB-A receiver in order to work. (Connection distance within 33 feet)
  • 【LARGE SIZE STANDARD ERGONOMIC AND FULL SIZE LAYOUT】Designed with a concave curve, which conforms to the natural shape of the hands and fingers, reducing strain and fatigue. In addition, each key is slightly angled to promote a more natural typing motion and further alleviate stress on your fingers, hands, and wrists. Keyboard(19.09*10.04*1.83inch)Mouse (2.87*4.09*2.28inch)
  • 【PILLOWED WRIST REST】Featured a pillowed palm rest, providing support and comfort for the hands and wrists. Made of a soft, non-slip material, preventing slippage and enhancing stability during typing. It reduce the risk of developing musculoskeletal disorders associated with prolonged keyboard use.
  • 【VERTICAL ERGONOMIC MOUSE】Unique vertical design offers optimal ergonomics, with adjustable DPI settings (800/1200/1600/2400)to suit various tasks and preferences, ensuring accuracy and speed when needed, a silent switch, and a side-scrolling wheel, catering to all your needs. The mouse and keyboard share a common USA-A receiver.
  • 【RECHARGEABLE AND LONG LASTING】 Featuring a 500mAh and 500mAh rechargeable battery in both the keyboard and mouse, providing long-lasting performance for extended use. The battery holds power for up to 1-2 months of usage on a single full charge. You can focus on work and worry less about charging. (Charge your keyboard and mouse before you use them. We recommend using the 5V 1A charging specification.).
N° 4
Wireless Keyboard and Mouse Combo, Ergonomic Wave Keys, Cushioned Plam Rest, Comfortable Silent Natural Typing, 2.4G Lag-Free, Full Size Keyboards Cordless Set for Multi-OS, Windows/Mac -SABLUTE
  • ERGONOMIC WAVE DESIGN: Meet the comfort with the wave keys ergonomic wireless keyboard. It reduces pressure for a more natural, superior typing experience. The adjustable leg stand option allows you to adjust the keyboard to the height that feels most comfortable, very suitable for computer workers.
  • INTEGRATED PALM REST: The wireless keyboard is equipped with a wrist rest made of comfortable leather, high-density support pads, and sturdy plastic bottom. It can better reduce hand pressure and provide you with better wrist support all day long.
  • LESS NOISE, MORE FOCUS: The silent micro-switch mouse effectively reduces 95% of noise, making the working environment quieter and no longer disturbing others.
  • EFFICIENT HOTKEYS & MOUSE: In addition to the regular F1-F12 shortcut hotkeys, our keyboard and mouse set equips you with 8 one-touch hotkeys on the wireless keyboard. Which paired with our 6-button mouse with 3-level tracking speed and forward/backward functions, can greatly improve your smoothness and efficiency of your page browsing at offcie/home/school/college work.
  • DUAL SYSTEM COMPATIBILITY: It is compatible with any device with a USB-A and USB-C port. In addition, you can switch between Windows and macOS using FN+A or FN+S.
N° 5
Logitech Wave Keys & Lift Vertical Mouse - Ergonomic Bundle — Wireless Keyboard with Cushioned Palm Rest & Vertical Wireless Mouse - Easy-Switch, Bluetooth, for Multi-OS, Windows/Mac - Rose
  • Feel the Wave. Feel the Lift: Wave Keys wireless ergonomic keyboard and Lift vertical ergonomic mouse are matched to turn your desk life into a feel-good story
  • Type in comfort all day long: This compact keyboard’s wavy design places your hands, wrists and forearms in a natural typing position for daylong feel-good
  • More palm support, less pressure: A cushioned palm rest with memory foam supports you all day long and gives you more wrist support(1)
  • Raise your hand into comfort: Small to medium hands feel great on Lift upright mouse, with a softly textured grip and snug thumb rest
  • Optimal 57° vertical angle: Lift’s vertical shape takes the pressure off your wrist, and promotes a more natural posture in the forearm for day-long comfort and productivity
N° 6
2.4GHz Wireless Vertical Ergonomic Mouse and Keyboard Combo Ultra-Thin Portable Size for PC Desktop Computer Laptop Mac Tablet
  • ERGONOMIC DESIGN: The mouse scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. The keyboard slope angle for comfortable use feeling, your hand will Not feel tired after using a while time. A good choice for people who work with the PC for a long time.
  • WIRELESS CONNECTIVITY: 2.4 GHz wireless technology with approximately 33 feet (10 meters) operating distance; One Nano USB receiver for both mouse and keyboard; You can find the receiver in the receiver compartment located on the backside of the keyboard.
  • FULL SIZE & ULTRA-THIN KEYBOARD: 17.72x5.91x1.57in with 101 Keys,ultra-thin enough to put it into your handbag or suitcase. Scissor-key-switch provide smooth typing and sensitive response, lowest volume keyboard keys and quiet mouse button.
  • 3 Adjustable DPI: 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Wide Compatibility: This wireless keyboard and mouse is support to work with windows, xp, mac os, vista, linux and other systems, but not suitable for ios system; The 12 hot keys on the keyboard are compatible windows system only.
PromoN° 7
MEETION New Ergonomic Keyboard and Mouse Wireless Combo, Wave Keys Natural Typing, 2.4G Wireless Keyboard with Wrist Rest, 4 Adjustable DPI Optical Mouse, Computer/Laptop/Windows/Mac, Black
  • 【WAVE KEYS FOR ULTIMATE COMFORT】 The wave-shaped keys are meticulously designed to align with the natural movement of your fingers. This design promotes a natural stretch and bend while typing, reducing finger fatigue and enhancing overall typing comfort, this product is a new version of the original Director-D.
  • 【ERGONOMIC WRIST REST】 Paired with the wave-shaped keys, the ergonomic wrist rest offers excellent wrist support. Its wave-like comfort reduces finger fatigue and wrist strain, providing a healthier, more comfortable typing experience for your hands.
  • 【WIRELESS CONVENIENCE, ANYTIME】 Experience the freedom of a 2.4GHz wireless keyboard and mouse combo. With a highly stable and interference-resistant connection, it's compatible with desktop PCs, laptops, and all-in-one PCs. Plug-and-play functionality ensures smooth operation for work or entertainment, wherever you are.
  • 【EXTENDED BATTERY LIFE】 The mouse operates on one AA battery, and the keyboard uses two AAA batteries, providing long-lasting performance. Say goodbye to frequent battery replacements and enjoy uninterrupted use, making this set ideal for both home and office environments. Stable output also extends the equipment's service life.
  • 【HIGH PRECISION AT YOUR FINGERTIPS】 The mouse features four adjustable DPI levels for customized precision. Easily switch between DPI settings using the convenient top button to adapt to various tasks and preferences—perfect for any workflow.
PromoN° 8
Wireless Ergonomic Keyboard and Mouse Combo with PU Wrist Rest, Carpal Tunnel Keyboard, 2.4G Colorful Split Ergo Keyboard, Comfortable Natural Typing, Compatible with PC/Laptop (Purple)
  • 【MEMBRANE ERGONOMIC KEYBOARD】Split and sloping keyboard design matches your arms and hands. The low keys can be activated with a light press, reducing typing stress. The integrated wrist rest supports your wrist in a comfortable position. This carpal tunnel keyboard allows you to type in a more natural posture, reducing muscle strain in your wrists and forearms.
  • 【WIRELESS CONNECTION】2.4G wireless transmission technology, the maximum transmission distance can reach 10m. The wireless connection solves the desktop clutter problem caused by the data cable, suitable for those who like to have a neat desktop. One USB receiver can connect the mouse and keyboard at the same time, reducing the occupation of the USB interface.
  • 【COMFORTABLE WRIST PAD】High-quality cushion and ergonomically tested palm rest covered in PU leather provides all-day comfort and promotes a neutral wrist posture.
  • 【3-LEVEL DPI ERGONOMIC MOUSE】 Press the DPI button to switch between 1200/1600/2400 DPI. By changing the DPI, you can adjust the cursor movement speed, making the mouse more suitable for your usage.(Default 1600 DPI). The part of the palm holding the mouse is covered with high-quality PU leather. More comfortable to hold and non-slip.
  • 【Product Guarantee】All of our products are inspected for quality before shipping. If there are quality issues with the product within one year of purchase, we offer a refund or a free replacement. If you have any questions, please feel free to contact us.
N° 9
Wireless Keyboard and Mouse Combo - Full-Sized Ergonomic Keyboard with Wrist Rest, Phone Holder, Sleep Mode, Silent 2.4GHz Cordless Keyboard Mouse Combo for Computer, Laptop, PC, Mac, Windows -Trueque
  • BUILT FOR COMFORT - Ergonomic keyboard designed with a generous palm rest and tilt legs, offers a better typing position to reduce the pressure on your wrist. The wireless mouse provides total comfort with a perfect handshake angle, contoured grips and premium matte finish.
  • FULL-SIZE KEYBOARD WITH HOLDER - Even when working with this keyboard mouse combo, you'll never miss any messages from your phone, since the built-in cradle can prop up your phone or tablet at a perfect angle to read or watch videos.
  • ENERGY SAVING & DURABILITY - Wireless mouse and keyboard features with smart sleep mode for saving power. Idle for 15 mins, the keyboard will sleep, idle for 10 mins, the mouse will sleep, press any button or key to wake up. You can go for months without the hassle of changing the batteries. The keyboard needs 2 x AAA battery, the mouse needs 1 x AA battery. (Battery Not Included)
  • LESS NOISE, MORE FOCUS - Soft membrane keys for making typing quiet and smooth. You can now enjoy quiet and comfortable typing all day long. The wireless mouse feels just as clicky but makes 95% less noise. No more worry about disturbing others.
  • NO DELAY, ENJOY WIRELESS FREEDOM - Plug and play, only one USB receiver for both keyboard and mouse! Upgraded chips and 2.4GHz wireless technology provide a stable and reliable connection up to 33ft without any latency.
PromoN° 10
SABLUTE Ergonomic Wireless Keyboard and Mouse Combo - Wave Keyboard with Soft Leather Wrist Rest, Resistant Keys, RGB Backlit Rechargeable Set for PC/Mac/Chromebook (Black)
  • FULL-SIZE ERGO WIRELESS KEYBOARD: Enjoy a precise typing experience with a familiar layout featuring a cushioned palm rest and thoughtfully designed keys. Upgraded UV Cured Wear-Resistant Keys, spill-resistant design, adjustable tilt feet, and easy-access media keys
  • WIRELESS WAVE KEYBOARD: Experience a new level of comfort with our wave-shaped ergonomic keyboard and mouse combo. Designed to support your natural hand position, the wave-shaped keyboard reduces strain
  • All-DAY PALM SUPPORT: A leather-cushioned palm rest ergo keyboard with memory foam provides lasting wrist support. The 4° or 7° adjustable typing angle lets you find the perfect height, while the ergonomic wireless mouse offers a natural grip for effortless control
  • ILLUMINATE YOUR WORKSPACE: The wave ergonomic wireless keyboard features 7 switchable backlights, paired with an RGB mouse that automatically changes colors. Even in the dark, the illuminated keys make typing easy. Adjust the brightness or turn off the lights anytime to save power
  • USB-C QUICK CHARGING: The rechargeable wireless keyboard mouse stays powered for up to 5 days on a full charge (2 months with backlighting off). The mouse lasts up to 6 days on a full charge. Includes auto-sleep mode and independent ON/OFF switches for efficient energy use

Frequently Asked Questions (FAQ)

What is the best ergonomic keyboards and mice?
It depends on your needs, but the top 3 products are generally the most balanced options.

How do I maintain it properly?
It varies by model. The best approach is to follow the manufacturer’s recommendations (yes, reading the manual is worth it).

Where to buy it with confidence?
Amazon remains a solid choice: wide selection, easy returns, and tons of user reviews—hard to beat.

Do I need a big-name brand?
Not necessarily. Lesser-known brands can be surprisingly good, with well-designed products that rival top names—at a lower cost. Don’t overlook them just because the name is unfamiliar.

What are the most common pitfalls?
A super low price might be tempting but could signal major compromises (build quality, reliability, nonexistent support…). Also beware of product pages with no reviews or vague comments. Spend a few minutes reading real feedback—this is often where the most valuable info is.

How is our ranking built?

We don’t claim to have a magic formula. In reality, it’s a blend of data—ratings, sales volume, review frequency—and observation. We watch for recurring themes in reviews, compare search trends, and yes, sometimes rely on our gut feeling. A great product isn’t just numbers. Our ranking aims to balance all of that: data, common sense, and a lot of time spent checking.

We analyze scores, sales frequency, genuine reviews (not just stars), and current search trends. Each model is rated using a consistent set of criteria. While it’s not perfect, it helps us stay fair and consistent. And we update our lists often, because products evolve—and so do we.

Why trust Topelio?

Topelio is an independent website—we don’t sell these products and we’re not tied to any brand. What drives us is clarity and usefulness. We aim to produce practical, readable, honest content. Our rankings are based on public data, complemented by our own experience. No shady partnerships or biased recommendations—just a genuine effort to save you time, and maybe money too.

See all ergonomic keyboards and mice on Amazon

Conclusion

Thanks for taking the time to read this guide. Choosing a ergonomic keyboards and mice might seem trivial, but it’s often more complicated than expected. Too many options, unclear product pages, and marketing promises that don’t help… That’s why we aimed to create a simple but solid comparison. With practical info, useful tips, and most importantly—a ranking based on reality. Take time to compare, read more reviews if needed, and choose based on your own priorities. What works for someone else might not be ideal for you. If this guide helped you, feel free to explore our other articles. We always try to add real value—without wasting your time. See you soon on Topelio.

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